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Marijuana May Turn Off DNA Linked To Skin Cancer, Allergies

By on September 4, 2013
Researchers say chemicals in marijuana may be able to switch off harmful DNA activity that underlies skin disease.

Researchers say ingredients in marijuana may be able to interfere with harmful DNA activity in skin cells

TruthOnPot.com – Marijuana may be the key to treating a wide range of skin diseases at the gene level, according to new research from Italy.

The study, published online in the British Journal of Pharmacology, shows that chemicals in marijuana have the potential to stop harmful DNA activity that underlies diseases like skin cancer and allergies.

“Our findings may lead to the development of preventive medicines, for example aimed at controlling allergic reactions, or to the design of new and more effective treatments for skin cancer.”

Certain genetic factors are believed to play a role in the uncontrollable growth of skin cells – a key characteristic of many disorders.

But a class of chemicals produced by marijuana called cannabinoids appears to have an unique ability of switching them off.

“Plant-derived cannabinoids that are absent of psychoactive effects may be useful candidates for these applications.”

In the study, researchers recorded the effects of three cannabinoids – cannabidiol (CBD), cannabigerol (CBG) and cannabidivarin (CBV) – on human skin cell lines.

CBD was found to be the most effective at targeting unwanted DNA activity, followed by CBG.

While THC has also been suggested as an effective therapy for skin allergies, research is beginning to focus on compounds in marijuana that can’t get you high – which may be more appealing to patients.

The authors also conclude that the potential to switch off gene activity may “extend well-beyond skin disorders” to diseases like multiple sclerosis and other forms of cancer.

The study was published ahead of print and received funding from GW Pharmaceuticals

  • Charles Waller

    Unlike the current pharmacological model, cannabinoid replacement therapy is dependent on the synergistic, or entourage, effect of the entire range of plant compounds found in cannabis. The fact that only a handful of cannabinoids has been studied to any degree demonstrates that it is premature to point to specific, singular cannabinoids as being capable of achieving the therapeutic benefits demonstrated by whole plant cannabis extract oil demonstrated in western research from Dr. W.B. O’Shaughnessy in 1839 to the present.

    • Tom-André Larsen

      Very good point. CBD might do some real work, but when you take out all the other cannabinoids from the mix, CBD won’t pack the same punch against dna defects and such.

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  • Stephen

    The study you cited does not support what you are claiming in this article.

    It sure sounds good though.

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  • ELUDZ

    FUCK OFF WITH ALL THE ‘MAY’ THIS AND ‘MAY’ THAT.. how come there are studies to prove things and data.. and the word ‘MAY’ is still being used in EVERY FUCKING article to do with medical cannabis..

    • Mulrich

      Because all science comes with a margin of error. That’s why result are evaluated in terms of probability. Correlation does not equal causality. Ethics and law require this research be done observationally not in clinical type 1 trials. Your ignorance of scientific understanding is typical of the public “at-large”, but is frustrating for people like myself with graduate-level training in research. Free speech is valuable but often cringe-worthy. What’s with all the anonymous anger on the Internet?

      • Jerry

        Mulrich, I think Eludz’s frustration comes from the fact that Science tends to have people who are suffering waiting for their approval which often takes years. Sometimes people know from direct experience what works and what doesn’t, and they grow impatient waiting. For instance, we know ET exist and have visited our planet for thousands of years, yet we are told there is no evidence. We know hemp oil in the form of THC cures cancer, but nothing is said about this because big pharmaceutical companies wish to profit from patented medicines. We know we are being sprayed with aerosol sprays daily, yet we are told there is no evidence. I hope you can understand the frustration of becoming sicker while science moves on very slowly as people suffer and die waiting for their approval. Sometimes it’s best to just dive in and try something that we know to be safe and has healing benefits. Let the people decide for themselves if they wish to experiment on themselves.

        • lisaparmeter

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