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What is CBD?
TruthOnPot.com – Cannabidiol (CBD) is one of the major ingredients found in the Cannabis plant. It belongs to a larger class of chemicals called cannabinoids.
Unlike THC, CBD is non-psychoactive, which means that it can’t get you high.
CBD was first isolated by scientists in 1940, but its structure was not identified until 23 years later.
Although scientists have identified over 60 different cannabinoids in the marijuana plant, CBD is present in abundant levels and represents up to 40% of cannabis extracts.
Like THC, the concentration of CBD is highly variable from strain to strain. CBD levels are suggested to have declined over past years due to the preference and selective breeding of marijuana with higher THC levels in the underground market.
Effects of CBD
CBD doesn’t act on CB1 receptors — the pathways responsible for the marijuana high — and therefore has no psychoactive properties. This single factor makes CBD a much more useful compound, both legally and medicinally.
In addition to being non-psychoactive, CBD has even been found to counteract a number of the psychoactive effects of THC. Studies have shown CBD to lessen the hallucinogenic effects of THC, block THC’s interference with memory and decrease social isolation induced by THC.
Strains and pharmaceuticals (such as Sativex) that balance THC with high CBD levels are able to enhance the benefits of THC while reducing its negative psychoactive effects.
Safety of CBD
Many studies have been conducted on CBD to evaluate different aspects of its safety. Some of the findings include:
Embryonic Development – Studies conducted to evaluate the safety of CBD intake for pregnant mothers found it to have no significant effect on developing embryos.
Food Intake – Studies have found that, unlike THC, CBD does not increase food intake. A study found that chronic administration of CBD for up to 2 weeks actually reduced weight gain in rats, suggesting that CBD may have the opposite effect of THC on food intake.
Motor Changes – Studies have not found CBD to induce motor changes, unlike THC.
Physiological Effects – CBD seems to have no effect across a wide range of physiological measures, including blood pressure, heart rate and body temperature.
CBD, like THC, is remarkably non-toxic and no human overdose has ever been recorded.
Medical Uses of CBD
CBD possesses an incredibly wide range of medicinal properties, similar to THC. However, CBD is not psychoactive and thus has a clear advantage over THC for use as a medicine. Studies have demonstrated CBD to exhibit the following list of therapeutic properties:
Anti-inflammatory – making it useful in treating multiple sclerosis and other neuroinflammatory disorders
Anticonvulsant – making it useful in treating epilepsy
Antiemetic (anti-nausea) – making it useful in treating chemotherapy and AIDS patients
Anti-tumoral – making it useful in fighting various forms of cancer
Antipsychotic – Making it useful in treating schizophrenia
Anxiolytic (anti-anxiety) and Anti-depressant – making it useful in treating anxiety and depression disorders
Anti-oxidant – making it useful in treating Parkinson’s Disease, Huntington’s Disease and numerous other neurodegenerative disorders
Sleep-inducing – making it useful in treating various sleep disorders
Despite its potential as a therapeutic agent in so many disorders, current research is still in the early stages and has yet to progress to clinical trials for the vast majority of listed conditions. Unfortunately, the legal status of CBD and its close association with marijuana continue to hinder its progress towards widespread access and use of CBD as a medicine.